2-MeSADP | 2-MeSADP | 2-MeSADP | 2-MeSADP | |
---|---|---|---|---|
+TEA | +IbTX | +Apamin | ||
gmin (nS) | 0.02 | 0.08 | 0.01 | 0.02 |
gmax (nS) | 4.86 | 3.84 | 4.17 | 2.41 |
z | 2.91 | 1.95 | 2.9 | 4.41 |
V1/2 (mV) | −14.2 | 0.39 | −1.07 | −14.7 |
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Values for maximum value for the voltage-dependent conductance (gmax), equivalent charge (z), and membrane potential at which 1/2 of gmax is reached (V1/2 ) obtained by fitting the 2-(Methylthio) ADP trisodium salt (2-MeSADP)-activated conductance (n = 62), tetraethylammonium (TEA)-sensitive conductance (n = 8), iberiotoxin (IbTX)-sensitive conductance (n = 12), and apamin-sensitive conductance (n = 11). gmin, minimum value for the voltage-dependent conductance.